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UCT Clinical/Forensic SPE Products


UCTĺs Clean Screen« columns are the most recognizable UCT product line. Columns in this line are the industry standard for mixed-mode solid-phase extraction for drugs of abuse and clinical drugs. Analytical demand for more efficient, robust and clean extraction of drugs from biological matrices led to the development of the Clean Screen DAU sorbent. Since 1986, The Clean Screen« line has led the industry with dependable and reproducible Solid Phase Extraction products and applications.

Many Clean Screen« phases are true copolymeric sorbents that contain hydrophobic and ion exchange functional groups uniquely polymerized to a silica substrate. The design and quality of Clean Screen« provides superior sample clean up, recovery and reproducibility. Mixed-mode separations allow maximum selectivity for extraction of acids, neutrals and bases. This selectivity makes Clean Screen« ideal for both screening and confirmation analysis for virtually all drug categories. Clean Screen«​ DAU and THC columns are used extensively by forensic and clinical chemists including Post Mortem Investigations, Criminal Investigations, Urine Drug Testing, Athletic Drug Testing, Animal Racing Laboratories, Therapeutic Drug Monitoring, & Medical Drug Screening.
DAU   THC   ETG   BNZ   GHB   Downloads 

CLEAN SCREEN« DAU is a copolymerized sorbent, utilizing both a reverse (C8) phase and an ion exchange (benzenesulfonic acid) phase bonded to the same particle. The mixed mode nature allows for maximum selectivity for the extraction of acids, neutrals and bases. This flexibility and versatility is ideal for both screening and confirmation analyses of virtually all drug categories.

Chemical Phase = C8 + BCX
Organic Loading = 12.4%
Average Pore Size = 60┼
Cation Exchange = 0.077 meq/g
Surface Area = 500 m2/g
Pore Volume = 0.77 cm3/g

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CLEAN SCREEN« THC sorbent is copolymerized on a rigid, purified silica gel support.  The two functional groups include a reverse phase and a primary amine ion exchanger.  This sorbent is useful for analyzing THC and its metabolites.  Additionally, its dual functionality is useful for acids and hydrophobic compounds.

Chemical Phase = NAX + C8
Organic Loading = 12.1%
Average Pore Size = 60┼
Anion Exchange = 0.144 meq/g
Surface Area = 500 m2/g
Pore Volume = 0.77 cm3/g

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CLEAN SCREEN« ETG solid phase extraction sorbent is available exclusively from UCT. It is a proprietary carbon packing material for the extraction and concentration of ethyl glucuronide. Sample extracts can be analyzed by either GC/MS or LC/MS.

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CLEAN SCREEN« BNZ solid phase extraction sorbent is a unique sorbent designed for benzodiazepine extractions, with specific focus on 7-amino clonazepam.

Chemical Phase = Proprietary
Organic Loading = 10.8%
Average Pore Size = 60 ┼
Surface Area = 500 m2/g
Pore Volume = 0.77 cm3/g

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CLEAN SCREEN« GHB sorbent is used for the extraction of free Gamma-hydoxy butyric acid (GHB).  The small polar nature of the molecule and the lack of a UV chromaphore complicate the chromatographic and spectrophotometric analysis of GHB.  Chemically, GHB is unstable and readily forms Gamma-butyrolactone when heated in acid conditions.  Most analytical methods are based upon the interconversion to the lactone and chemical derivatization to form the TMS derivative.  This sorbent isolates and extracts free GHB.

Chemical Phase = Proprietary
Organic Loading = 12.1%
Average Pore Size = 60┼
Surface Area = 500 m2/g
Pore Volume = 0.77 cm3/g

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