ChromegaChiral CC2 is a modified cellulose including 3-chloro-4 methylphenyl-carbamate bonding groups coated on high purity, high performance spherical silica particles. This combination of bonded groups stabilizes the solubility of coated phase making for a durable phase similar to other widely used coated phases and provides for similar separation behavior to Phenomenex Lux® Cellulose-2.