ChromegaChiral CCO F2 – The addition of a fluorine atom into a phenyl carbamate cellulose structure can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds (1). A fluorophilic retention mechanism can be particularly useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine (2). ChromegaChiral CCO F2 is a 2-Fluoro 5-methylphenyl cellulose phase which can be used in SFC or HPLC.